Sedation and Analgesia in ICU
Agents used for sedation in ICU
Some general points:
There is not a single universally accepted ICU sedation protocol, therefore many units have their own which you should seek out and familiarise yourself with.
Most ICU patients will encounter painful or uncomfortable stimuli as a consequence of their illness or management, therefore analgesia should almost always be provided with sedation.
All sedative drugs should be titrated (both up and down) to a target sedation score.
When increasing the rate of a sedative infusion, a bolus dose should be given to achieve a more rapid attainment of an adequate, steady state effect site (brain) concentration.